Autophagy is mostly recycling proteins in the cell due to low availability of amino acids, so it is interrupted by protein intake and arguably carbs too (because no carbs means the liver will need to use protein for gluconeogenesis). of coconut oil: 120 calories and 14 grams of fat; Even if you put a splash of cream in your coffee you will still be okay. Does fat interfere with autophagy during fasting? Eating protein or carbs will quickly stop autophagy and other beneficial fasting-stimulated metabolic processes. Your body is releasing and running on stored fat anyway during a fast. So this process of autophagy is unique to fasting – something not found in simple caloric restriction or dieting. Dr. Jason Fung They work by various, diverse means. It also promotes autophagy, the process by which your body rids itself of unneeded, damaged, or harmful cells (5, ... coconut oil, or butter during their fast. Likely not, although research is lacking. Autophagy helps to create a stronger and more resilient body and mind. "A fast is broken with consumption of food or a caloric substance; however, many people who enjoy the benefits of fasting and want to incorporate it as a daily ritual may take a more flexible approach such as a 'fat fast' using coconut oil, MCT oil, grass-fed butter, or cacao butter blended into a warm liquid during their fasted window." Autophagy Creates a Stronger and More Stress Resilient Body and Mind. Nicholas. Autophagy mostly turns off with protein. HWC has some carbs (0.4g per Tbsp, IIRC), and a small amount of protein. Cortisol is the stress hormone, so when fasting in a highly stressed state you could actually prevent autophagy. Autophagy, however, is a clean and energy-efficient process that doesn’t lead to inflammation. IIRC fat intake doesn't stop autophagy. Researchers believe that autophagy has huge anti-ageing benefits. When autophagy fails, beta cells in your pancreas accumulate oxidative damage and eventually stop being able to produce insulin[*]. A few of the heavyweights in the world of autophagy and aging research have put together a nice compendium of chemical autophagy inducers: Caloric restriction mimetics: natural/physiological/ pharmacological autophagy inducers. Autophagy Summary Autophagy translates to “self-eating.” It’s a beneficial process that involves the removal and recycling of the body’s own tissue as a metabolic process. There is a balance here, of course. Autophagy enhancers boost the health effects of intermittent fasting. Even a small amount of amino acid (leucine) could stop autophagy cold. Even consuming pure fat like coconut oil or olive oil requires the gut and liver to be recruited for processing, which essentially is a a signal to your cells to slow autophagy. It helps cleanse waste from the body, provides energy and can stave off chronic illnesses. Hello Jason, Specifically, does coconut oil, being 100% fat only and little else, have an effect on autophagy when it keeps ketones high as well? Relying on activating autophagy is a much better way of recycling old cells (6). 1 tbsp. Of course, glucose and proteins will stop autophagy, as well as cortisol. Coconut oil will not cause your insulin levels to rise. Oil … Better, if you want to supplement with fat, to stick with grass-fed butter, coconut or MCT oil. You get sick from too much autophagy as well as too little. But coconut oil and MCT oil are not the same things. Fasting works because it keeps your insulin levels low enough to allow fat burning (oxidation) to occur. From what @richard has said in a couple of threads, HWC may be problematic if your goal (or a goal) for fasting is triggering autophagy. Which gets us back to the natural cycle of life – feast and fast.
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